Abiel s.r.l. is a biotechnology company founded in 2010 as a spin-off of Palermo University and C.N.R. (National Research Council). The founders have identified a strong demand for pure, stable and well-characterized tissue dissociation enzymes for cell therapy and regenerative medicine applications. Abiel fulfils these unmet needs synthesizing and commercializing stable, highly pure and toxic-free recombinant collagenases (COL G class I and COL H class II). Abiel also provides services and R&D in the field of lytic enzymes, particularly the screening, characterization and production of new enzymes from biomarine resources for industry. Abiel aims to become an international leader in the discovery, development and marketing of innovative value-added lytic enzymes for regenerative medicine, biopharmaceutical and industrial applications.
ABIEL is composed by a multidisciplinary team of qualified scientists and professionals in the field of enzymes and microbiology, by endocrinologists specialized in cell therapy and regenerative medicine, and by specialists in monitoring and business development.
Giulio Ghersi Associate Prof. in Biological Chemistry
He is expert in enzymology and in particular expert in proteolytic enzymes. Since 1995, he has studied the role, function and structural-functional organization of proteolytic enzymes in the processes of cell motility/invasiveness. He has presented in many international and national conferences on the topic of proteolytic enzymes and he has published important articles in prestigious scientific journals including Cancer Research, Advances in Experimental Medicine and Biology and The Journal of Biological Chemestry. He was also a Professor in the ICRA UNESCO International Training Course. Finally, he is referee for the international scientific journals Oncology and Biological Chemestry.


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Camillo Ricordi MD in Endocrinology
Director and Chief Academic Officer of the Diabetes Research Institute (Miami) and distinguished Professor of Medicine and Surgery, Biomedical Engineering, Microbiology and Immunology at the University of Miami Miller School of Medicine. Acknowledged by his peers as one of the world's leading scientists in cell transplantation, Dr. Ricordi is well-known for developing the Automated Method for Islet Isolation. The procedure made it possible to isolate large numbers of pancreatic islets and is now used by laboratories performing clinical islet transplants worldwide. Dr. Ricordi was founder and president of the Cell Transplant Society (1992-94), co-founder of the National Diabetes Research Coalition (Chairman 1997) and president of the International Association for Pancreas and Islet Transplantation (1999-2001; IPITA). He has received numerous honors and awards, including the 2001 Nessim Habif World Prize of Surgery (University of Geneva) for developing a machine and a technology that significantly contributed to the advancement of a surgical field. He has been serving on the editorial boards of several scientific journals, including Cell Transplantation (Editor-in-Chief), American Journal of Transplantation (Associate Editor), Transplantation, Transplantation Proceedings, and Tissue Engineering. Dr. Ricordi has authored more than 500 scientific publications. As inventor, he was awarded nine patents.


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Monica Salamone PhD in Cell Biology
She is expert in proteolytic enzymes. She started her research in biochemistry studying molecules involved in the cell-cell and cell-matrix adhesion of sea urchin embryo and afterwards of normal or cancerous human cells cultivated in vitro. In addition to the adhesion molecules she studied the human collagenases, both of the family of metalloproteases and serine proteases. She performed part of her studies in America in the laboratory of Prof. Chen Wen Tien at the Lombardi Cancer Center. For two years she studied proteins and proteolytic enzymes with microbial and marine origin to use for both research purposes and pharmaceutical industries. In particular her focuses are collagenases and proteases from marine microorganisms through enzymology techniques. She spent time in Miami at the Diabetes Research Institute - University of Miami Miller School of Medicine, where she was updated on the techniques of cell enzymatic extraction from pancreas of rodents, purification of Langerhans islets and related techniques. She is author of important publications in important scientific journals.


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Gregorio Seidita Researcher in Applied Biology
PhD in cell and developmental biology. He is specialist in medical genetics, molecular biology and in particular in the synthesis of recombinant proteins; He is also a scientific technical consultant and specialist in forensic genetics. From many years he works at the University of Palermo as a teacher of genetic and applied molecular genetic in different Biotechnology courses. He is author of important publications in leading scientific journals of molecular genetics including The American Journal of Medical Genetics.


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Federico Bertuzzi MD in Endocrinology
He is specialist in the isolation and transplantation of Langerhans islet in patients with mellitus diabetes type 1. Since 1989, he has worked on the digestion of pancreas with the aim of isolating the pancreatic islets, first as a student (until 1990), then as a researcher (until 1996) and finally as manager of the functional unit at the San Raffaele Scientific Institute in Milan (until 2006) and also as head of the Diabetes Unit at the Mediterranean Institute for Transplantation and Highly Specialized Therapies (ISMETT) of Palermo. Currently he is working at Niguarda Hospital in Milan at the Diabetes Unit with a highly specialized focus. He is authorized by AIFA as technical director of workshops for cell therapy and he is inspector of the National Transplants Center for the Tissues Banks. He's expert in transplantation and regenerative medicine and therefore he has lectured in many national and international conferences. He is a member of the editorial committee of Transplantation, Cell Transplantation and Current Molecolar Medicine, he also works as editorial reviewer for numerous scientific journals including Diabetes, The Lancet, American Journal of Transplantation, European Journal of Endocrinology and Journal of Cellular and Molecular Medicine.


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Angela Cuttitta CNR Researcher
She is expert in marine biology and in planning. From many years she has been committed to studying and monitoring the marine environment. She is a qualified researcher who had participated in many national and European projects of industrial and fundamental research, dissemination of scientific culture and education. She has numerous publications in important scientific journals, she has participated in leading European conferences, and she is inventor of several international patent applications. She also worked in FAO as trainer in different training courses on the management of marine biological resources.


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Salvatore Barbagallo Business Development Manager
Salvatore Barbagallo has over 30 years experience in the pharmaceutical industry. He started as hospital sales representative and medical science liaison for Upjohn and then joined Cyanamid Lederle Italy as product manager . After he increased his responsibilities as marketing manager of Lederle products and director of Lederle-Praxis vaccine business unit. Following Cyanamid's acquisition he moved to Rome where he served Wyeth Italy as responsible for Licensing & Business Development leading successful divest projects as well as some in-licensing domestic opportunities. During the last 5 years he broadened his experience in R&D as project leader of several research projects carried out at Wyeth EDSM Research center, Catania site in collaboration with European Universities, MUR (Italian Ministry of University & Research) and National Council of Research . He holds a degree magna cum laude in Chemistry at the University of Catania and a degree in Pharmacy.


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Alessandra Lo Cicero Product Manager
Biotechnologist specialized in biotechnology for industry and scientific research, with a PhD in Oncobiology. She worked one year at the Imperial College in London and 4 years at the Institute Curie in Paris, studying the role of extracellular vesicles in pathological and physiological conditions. She has acquired expertise in the field of cell therapy and drug discovery working for 18 months at I-STEM, the Institute for Stem cell Therapy and Exploration of Monogenic diseases in Evry, generating pluripotent stem cells form progeriaís patients and preparing a high throughput screening campaign of pharmacological compounds in order to identify new treatments of this disease. She is author of numerous publications in important scientific journals.


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CNR-IAMC Capo Granitola (TP)